MLB Sleeper Fantasy Player Predictions for Wednesday (5/6)
Wednesday, May 6, 2026: Below are three of the best picks for today’s MLB slate on Sleeper Fantasy according to our projections team. Using factors like advanced analytics, minutes, matchups, and pace, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.
Keep in mind that the NBA news cycle can get crazy, so what is listed below may become a better/worse play depending on how news breaks. Be sure to keep close tabs on our NBA starting lineups page and NBA injury report to get a current snapshot of who is in/out and what a team’s rotation and depth chart looks like.
Below, I’ll detail how I’m approaching things on Sleeper Fantasy for this Wednesday slate.
First… Sign Up to Make MLB Sleeper Fantasy Picks
If you want to play along but haven’t signed up yet, grab a special offer with our Sleeper Fantasy promo code to unlock a generous bonus. Sleeper Fantasy – one of the most popular DFS pick’em sites – provides player projections for MLB matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.
When making your MLB Sleeper picks today, let RotoGrinders do the heavy lifting for you!
Sleeper Fantasy Top MLB Picks for May 6, 2026
Now that you’re signed up, here are some of our top NBA DFS picks on Sleeper Fantasy for Wednesday:
- Shane McClanahan less than 4.5 Pitcher Strikeouts
- TJ Friedl more than 1.5 Hits + Runs + RBIs
- Xavier Edwards more than 1.5 Total Bases
Blue Jays vs. Rays MLB Sleeper Fantasy Predictions
Shane McClanahan less than 4.5 Pitcher Strikeouts
The pitcher strikeouts projection for Shane McClanahan looks like a strong pick based on the current data. The Sleeper projection of 4.5 compares favorably based on our MLB simulations. This pick projects to hit 56.7% of the time based on the assumptions, and that represents a 8.7% edge.
Reds vs. Cubs MLB Sleeper Fantasy Predictions
TJ Friedl more than 1.5 Hits + Runs + RBIs
The hits + runs + RBIs projection for TJ Friedl looks like a strong pick based on the current data. The Sleeper projection of 1.5 compares favorably based on our MLB simulations. This pick projects to hit 56.3% of the time based on the assumptions, and that represents a 7.5% edge.
Orioles vs. Marlins MLB Sleeper Fantasy Predictions
Xavier Edwards more than 1.5 Total Bases
The total bases projection for Xavier Edwards looks like a strong pick based on the current data. The Sleeper projection of 1.5 compares favorably based on our MLB simulations. This pick projects to hit 57.4% of the time based on the assumptions, and that represents a 5.6% edge.
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Image Credit: Imagn