MLB Underdog Player Predictions for Wednesday (5/6)
Wednesday, May 6, 2026: Below are three of the best picks for today’s MLB slate on Underdog according to our projections team. Using factors like Statcast data, advanced sabermetrics, weather impacts, and environmental factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.
Don’t forget to check out our MLB weather page to see how that may impact these picks as the day progresses. And you can always stay up to date on exactly what a team’s lineup is by heading to our MLB starting lineups page.
Below, I’ll detail how I’m approaching things on Underdog for this Wednesday slate.
First… Sign Up to Make MLB Underdog Picks
If you want to play along but haven’t signed up yet, grab a special offer with our Underdog promo code to unlock a generous bonus. Underdog – one of the most popular DFS pick’em sites – provides player projections for MLB matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.
When making your MLB Underdog picks today, let RotoGrinders do the heavy lifting for you!
Underdog Top MLB Picks for May 6, 2026
Now that you’re signed up, here are some of our top MLB DFS picks on Underdog for Wednesday:
- Brandon Young lower than 3.5 Pitcher Strikeouts
- Will Warren lower than 6.5 Pitcher Strikeouts
- Cole Ragans lower than 5.5 Pitcher Strikeouts
Orioles vs. Marlins MLB Underdog Predictions
Brandon Young lower than 3.5 Pitcher Strikeouts
The strikeouts projection for Brandon Young looks like a strong pick based on the current data. The Underdog projection of 3.5 compares favorably based on our MLB simulations. This pick projects to hit 62.5% of the time based on the assumptions, and that represents a 6.4% edge.
Rangers vs. Yankees MLB Underdog Predictions
Will Warren lower than 6.5 Pitcher Strikeouts
The pitcher strikeouts projection for Will Warren looks like a strong pick based on the current data. The Underdog projection of 6.5 compares favorably based on our MLB simulations. This pick projects to hit 73.1% of the time based on the assumptions, and that represents a 1.7% edge.
Guardians vs. Royals MLB Underdog Predictions
Cole Ragans lower than 5.5 Pitcher Strikeouts
The pitcher strikeouts projection for Cole Ragans looks like a strong pick based on the current data. The Underdog projection of 5.5 compares favorably based on our MLB simulations. This pick projects to hit 53.6% of the time based on the assumptions, and that represents a 1.5% edge.
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