NFL PrizePicks Player Predictions for Chiefs vs. Jaguars MNF (10/6)
Week 5, Monday Night Football: Below are three of the best picks on PrizePicks according to our projections team for the Chiefs vs. Jaguars game on October 6, 2025. Using factors like advanced participation data, the latest efficiency analytics, historical trends, and advanced matchup factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.
Don’t forget to check out our NFL weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks. And you can always stay up to date on exactly what a team’s depth chart is looking like by heading to our NFL starting lineups page.
Below, I’ll detail how I’m approaching things on PrizePicks for Chiefs vs. Jaguars.
First… Sign Up to Make NFL PrizePicks Picks
If you want to play along but haven’t signed up yet, grab a special offer with our PrizePicks promo code “GRINDERS” to get $50 on a $5 entry! PrizePicks – one of the most popular DFS pick’em sites – provides player projections for NFL matchups each week. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.
When making your NFL PrizePicks picks today, let RotoGrinders do the heavy lifting for you!
PrizePicks Top NFL Picks for Chiefs vs. Jaguars
Now that you’re signed up, here are some of our top NFL DFS picks on PrizePicks for Monday Night Football:
- Patrick Mahomes more than 23.5 Passing Completions
- Xavier Worthy more than 4.5 Receptions
- Parker Washington more than 15.5 Receiving Yards

Chiefs vs. Jaguars NFL PrizePicks Predictions
Patrick Mahomes more than 23.5 Passing Completions
The passing completions projection for Patrick Mahomes looks like a strong pick based on the current data. The PrizePicks projection of 23.5 compares favorably based on our NFL simulations. This pick projects to hit 57.5% of the time based on the assumptions, and that represents a 3.2% edge.
Xavier Worthy more than 4.5 Receptions
The receptions projection for Xavier Worthy looks like a strong pick based on the current data. The PrizePicks projection of 4.5 compares favorably based on our NFL simulations. This pick projects to hit 57.3% of the time based on the assumptions, and that represents a 3.0% edge.
Parker Washington more than 15.5 Receiving Yards
The receiving yards projection for Parker Washington looks like a strong pick based on the current data. The PrizePicks projection of 15.5 compares favorably based on our NFL simulations. This pick projects to hit 56.4% of the time based on the assumptions, and that represents a 2.0% edge.
Editor’s Note: Looking for more places to play? Check out our Underdog promo code and PrizePicks promo code.
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