Million Dollar Musings: MLB DFS Picks Today for Monday 5/25

by Dave Potts (CheeseIsGood) Last Updated 2026-05-25 17:58:52 Premium Content Part of the product MLB DFS

Whether you are looking for the top pitchers or the best stacks, Dave Potts (aka CheeseIsGood) has you covered with an extensive deep dive into his MLB DFS picks today. Cheese, one of the preeminent baseball minds in all of fantasy sports and a winner of a $1,000,000 1st-place prize on both DraftKings and FanDuel, is here to give you his musings on the May 25, 2026 MLB DFS slate.

Happy Monday! This Memorial Day gives us games scattered all over the place, which is great for watching baseball but tougher for content and DFS. DraftKings is running an early 6-game slate that starts at 1:35 PM ET and then a 5-game slate that starts at 6:40 PM ET. Meanwhile, FanDuel is making their main slate a 6-gamer that starts at 6:10 PM ET. I will start with a look at the pitching-heavy early DK slate, and then we’ll be back after some more coffee with a look at those evening slates.

Monday Early Pitching: MLB DFS Picks on DraftKings

We have a pretty good pitching slate, headlined by the ridiculously elite Jacob Misiorowski, who belongs in his own tier up top.

THE MIZ TIER

• Jacob Misiorowski vs. Cardinals – 39.3 % K, 8% BB, 1.89 ERA, 2.21 SIERA

THE TOP TIER

• Shane McClanahan at Orioles – 25.8% K, 9.3% BB, 2.82 ERA, 3.69 SIERA
• Nolan McLean vs. Reds – 29.5% K, 7.3% BB, 3.57 ERA, 3.01 SIERA
• Will Warren at Royals – 28.2% K, 5.9% BB, 3.61 ERA, 3.00 SIERA

We’ve reached the point where Jacob Misiorowski is priced so far ahead of all the other pitchers that it is no longer enough that he is clearly the best pitcher on the slate. He is definitely the best pitcher on the slate. We’ve also long since passed the point where we have to pretend as if matchup matters for Misiorowski. If you want to find a reason other than salary to be wary of him, I guess it would be his workload. After he left 2 starts ago with leg cramps, he was pulled after 6 fantastic innings and 74 pitches in his last start. The official line from the manager was “he ran out of gas.” I guess one whole inning without a strikeout is so unusual that they assumed he must be tired. Honestly, I don’t know exactly what to take from this, but I think I have to say it’s more likely than not that they try to limit him to that range of 85-90 pitches rather than the 95-100 that he had early in the season. With that, he’s still far and away the best pitcher on the slate, but that does make him possibly not a must-play. Let’s see what else we find and then sort it all out.

Shane McClanahan finally gave up some runs in his last start, and really, he was due for some regression, but nothing changed about how he was pitching. He looks really good but is also still not all the way back to where he was before his injury. I think his current 25.8% K rate looks like a realistic expectation, and it also looks like the Rays are probably going to continue to be cautious with his pitch count in that way that only the Rays can do it. He can go 90 pitches, which means he can go 6 innings if everything goes his way, but they can also decide to just pull the plug after 5 innings regardless of pitch count if their weird little magic 8-ball (or whatever they use) tells them to. The Orioles are a good matchup for lefties, with 7 high-strikeout batters in their projected lineup. He looks correctly priced, and I am interested, but let’s see what else we find.

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