MLB PrizePicks Player Predictions for Thursday (9/11)

Gore of the Nationals

Thursday, September 11, 2025: Below are three of the best picks for today’s MLB slate on PrizePicks according to our projections team. Using factors like Statcast data, advanced sabermetrics, weather impacts, and environmental factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.

PropsPickEm_General_1284x700px

Don’t forget to check out our MLB weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks as the day progresses. And you can always stay up to date on exactly what a team’s lineup is by heading to our MLB starting lineups page.

Below, I’ll detail how I’m approaching things on PrizePicks for this Thursday slate.

First… Sign Up to Make MLB PrizePicks Picks

If you want to play along but haven’t signed up yet, grab a special offer with our PrizePicks promo code “GRINDERS” to get $50 on a $5 entry! PrizePicks – one of the most popular DFS pick’em sites – provides player projections for MLB matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.

When making your MLB PrizePicks picks today, let RotoGrinders do the heavy lifting for you!

PrizePicks Top MLB Picks for September 11, 2025

Now that you’re signed up, here are some of our top MLB DFS picks on PrizePicks for Thursday:

Add this pick with 1 click!PLACE THIS BET ONPRIZEPICKS

Nationals vs. Marlins MLB PrizePicks Predictions

MacKenzie Gore more than 4.5 Pitcher Strikeouts

The pitcher strikeouts projection for MacKenzie Gore looks like a strong pick based on the current data. The PrizePicks projection of 4.5 compares favorably based on our MLB simulations. This pick projects to hit 59.6% of the time based on the assumptions, and that represents a 5.3% edge.

Rockies vs. Padres MLB PrizePicks Predictions

McCade Brown more than 1.5 Walks Allowed

The walks allowed projection for McCade Brown looks like a strong pick based on the current data. The PrizePicks projection of 1.5 compares favorably based on our MLB simulations. This pick projects to hit 56.1% of the time based on the assumptions, and that represents a 1.7% edge.

Angels vs. Mariners MLB PrizePicks Predictions

Bryce Miller less than 5.5 Pitcher Strikeouts

The pitcher strikeouts projection for Bryce Miller looks like a strong pick based on the current data. The PrizePicks projection of 5.5 compares favorably based on our MLB simulations. This pick projects to hit 55.9% of the time based on the assumptions, and that represents a 1.6% edge.

Editor’s Note: Looking for more places to play? Check out our Underdog promo code and Sleeper promo code.

Image Credit: Imagn

About the Author

Jbails26
Justin Bailey (Jbails26)

Justin Bailey (aka jbails26) is the Lead Editor for RotoGrinders and FantasyLabs. He’s been playing DFS since 2013 and specializes in small-field NFL and PGA contests (but still dabbles in MME). Justin qualified for the DraftKings Fantasy Golf World Championship in 2023. Follow Justin on X – @justinbailey32