MLB PrizePicks Player Predictions for Thursday (9/11)
Thursday, September 11, 2025: Below are three of the best picks for today’s MLB slate on PrizePicks according to our projections team. Using factors like Statcast data, advanced sabermetrics, weather impacts, and environmental factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.
Don’t forget to check out our MLB weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks as the day progresses. And you can always stay up to date on exactly what a team’s lineup is by heading to our MLB starting lineups page.
Below, I’ll detail how I’m approaching things on PrizePicks for this Thursday slate.
First… Sign Up to Make MLB PrizePicks Picks
If you want to play along but haven’t signed up yet, grab a special offer with our PrizePicks promo code “GRINDERS” to get $50 on a $5 entry! PrizePicks – one of the most popular DFS pick’em sites – provides player projections for MLB matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.
When making your MLB PrizePicks picks today, let RotoGrinders do the heavy lifting for you!
PrizePicks Top MLB Picks for September 11, 2025
Now that you’re signed up, here are some of our top MLB DFS picks on PrizePicks for Thursday:
- MacKenzie Gore more than 4.5 Pitcher Strikeouts
- McCade Brown more than 1.5 Walks Allowed
- Bryce Miller less than 5.5 Pitcher Strikeouts

Nationals vs. Marlins MLB PrizePicks Predictions
MacKenzie Gore more than 4.5 Pitcher Strikeouts
The pitcher strikeouts projection for MacKenzie Gore looks like a strong pick based on the current data. The PrizePicks projection of 4.5 compares favorably based on our MLB simulations. This pick projects to hit 59.6% of the time based on the assumptions, and that represents a 5.3% edge.
Rockies vs. Padres MLB PrizePicks Predictions
McCade Brown more than 1.5 Walks Allowed
The walks allowed projection for McCade Brown looks like a strong pick based on the current data. The PrizePicks projection of 1.5 compares favorably based on our MLB simulations. This pick projects to hit 56.1% of the time based on the assumptions, and that represents a 1.7% edge.
Angels vs. Mariners MLB PrizePicks Predictions
Bryce Miller less than 5.5 Pitcher Strikeouts
The pitcher strikeouts projection for Bryce Miller looks like a strong pick based on the current data. The PrizePicks projection of 5.5 compares favorably based on our MLB simulations. This pick projects to hit 55.9% of the time based on the assumptions, and that represents a 1.6% edge.
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Image Credit: Imagn