NFL Preseason DFS Tiers & Core Plays: Week 2 - Friday Slate (8/21)

by Chris Gimino (ChrisGimino)

Created Aug 21, 2026

Last Updated 2026-08-21 17:47:31 Premium Content Part of the product NFL DFS

NFL DFS on DraftKings and FanDuel is back! This preseason, the RotoGrinders team will once again be producing NFL DFS picks, previews, and projections for everyone’s favorite daily fantasy sport. We’re here to cover the Week 2 preseason slate taking place on Friday, August 21, 2026.

Kyle Murray and Chris Gimino will be leading our team of NFL Preseason DFS fanatics to bring you their top selections. Our NFL experts track all of the depth charts and injury reports, in addition to any actionable information shared by coaches and beat writers, to help guide their DFS picks.

NFL Preseason DFS Picks: Tiers & Core Plays for the Week 2 Friday Slate

Friday’s three-game preseason slate is another exercise in prioritizing opportunity over name recognition. Defenses and kickers remain dependable building blocks, while the strongest skill-position targets are quarterbacks competing for jobs, healthy running backs positioned for extended workloads and pass catchers who still need game reps to secure roles. With several teams offering limited or deliberately vague playing-time guidance, tonight’s edge will come from reacting to final availability news and avoiding established players whose reputations outweigh their likely volume.

Recommended NFL Preseason DFS Tools:

• Preseason Injury Report and Depth Charts
• NFL DFS Optimizer (LineupHQ)
• NFL DFS Projections

Want to see the top picks and core plays? Sign up for NFL Premium!

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