NFL PrizePicks Player Predictions for Dolphins vs. Bills TNF (9/18)

Patterson of the Dolphins

Week 3, Thursday Night Football: Below are three of the best picks on PrizePicks according to our projections team for the Dolphins vs. Bills game on September 18, 2025. Using factors like advanced participation data, the latest efficiency analytics, historical trends, and advanced matchup factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.

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Don’t forget to check out our NFL weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks. And you can always stay up to date on exactly what a team’s depth chart is looking like by heading to our NFL starting lineups page.

Below, I’ll detail how I’m approaching things on PrizePicks for Dolphins vs. Bills.

First… Sign Up to Make NFL PrizePicks Picks

If you want to play along but haven’t signed up yet, grab a special offer with our PrizePicks promo code “GRINDERS” to get $50 on a $5 entry! PrizePicks – one of the most popular DFS pick’em sites – provides player projections for NFL matchups each week. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.

When making your NFL PrizePicks picks today, let RotoGrinders do the heavy lifting for you!

PrizePicks Top NFL Picks for Dolphins vs. Bills

Now that you’re signed up, here are some of our top NFL DFS picks on PrizePicks for Thursday Night Football:

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Dolphins vs. Bills NFL PrizePicks Predictions

Riley Patterson less than 8.5 Fantasy Points

The fantasy points projection for Riley Patterson looks like a strong pick based on the current data. The PrizePicks projection of 8.5 compares favorably based on our NFL simulations. This pick projects to hit 59.9% of the time based on the assumptions, and that represents a 5.5% edge.

Tua Tagovailoa more than 23.5 Passing Completions

The passing completions projection for Tua Tagovailoa looks like a strong pick based on the current data. The PrizePicks projection of 23.5 compares favorably based on our NFL simulations. This pick projects to hit 58.0% of the time based on the assumptions, and that represents a 3.7% edge.

Josh Allen more than 29.5 Rushing Yards

The rushing yards projection for Josh Allen looks like a strong pick based on the current data. The PrizePicks projection of 29.5 compares favorably based on our NFL simulations. This pick projects to hit 56.6% of the time based on the assumptions, and that represents a 2.3% edge.

Editor’s Note: Looking for more places to play? Check out our Underdog promo code and Sleeper promo code.

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About the Author

Jbails26
Justin Bailey (Jbails26)

Justin Bailey (aka jbails26) is the Lead Editor for RotoGrinders and FantasyLabs. He’s been playing DFS since 2013 and specializes in small-field NFL and PGA contests (but still dabbles in MME). Justin qualified for the DraftKings Fantasy Golf World Championship in 2023. Follow Justin on X – @justinbailey32