Giants vs. Bills Week 6 Showdown NFL DFS Lineup Advice for DraftKings & FanDuel

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Why can’t these Sunday Night Football matchups be more exciting? We have another massive spread, as Buffalo is more than a two-touchdown favorite in the Giants vs. Bills matchup for the Week 6 Showdown slate tonight. New York’s offensive line has been historically bad to start the season, and now they’re without their starting quarterback, as Daniel Jones is hurt and Tyrod Taylor takes the reigns. Pray for his health.

Giants vs. Bills Week 6 Showdown Lineup Advice

On both FanDuel and DraftKings, I’ll set a maximum of 2 Giants in RotoGrinders LineupHQ while loading up on full Bills onslaught teams in every single lineup. I’m going with the spread here and trusting the Bills to annihilate the Giants tonight. I’ll load up on the RBs on both sites, while Josh Allen will get the lock button, playing him either in the Flex or CPT / MVP position in every single lineup, using LineupHQ to make it work.

DraftKings Strategy

On DraftKings, it’s a lot easier to roll out a stars-and-scrubs lineup, as there are a plethora of cheap options. With Dalton Kincaid hurt, Dawson Knox should go back to similar usage to what he has seen in previous years, making him aggressively underpriced at $3,800. He will be a priority alongside Deonte Harty and Khalil Shakir to be able to afford as much James Cook, Stefon Diggs and Gabe Davis as possible alongside Josh Allen. Wan’Dale Robinson will be my favorite run back for the Giants, but I’ll use as many Bills as possible.

Favorite Large-Field CPTs: James Cook, Gabe Davis, Dawson Knox

Favorite Large-Field GPP Shots: Dawson Knox, Deonte Harty, Khalil Shakir, Damien Harris

FanDuel Strategy

Deonte Harty doesn’t provide the same type of salary relief on FanDuel as he does on DraftKings. However, Dawson Knox is still ridiculously underpriced. He’ll be my top priority for salary savings with Wan’Dale Robinson and Darius Slayton being my two favorite run backs for the Giants. James Cook is underpriced and will get the lock button for me on FanDuel, meaning I’ll be playing Josh Allen and James Cook together, either in the Flex or MVP, in every single lineup. I’ll also look to be overweight on the Bills defense, using the “Player Groups” and “Use Conditional Player” functions in LineupHQ to ensure that each time I have James Cook in the MVP, I also have the Bills defense.

Favorite Large-Field MVPs: James Cook, Gabe Davis, Stefon Diggs

Favorite Large-Field GPP Shots: Dawson Knox, Bills defense, Wan’Dale Robinson

Image Credit: Getty Images

About the Author

tjzwarych1
TJ Zwarych (tjzwarych1)

TJ Zwarych is a longtime RotoGrinders member and has been rising up the DFS rankings. He has been producing content for a long time, previously contributing to sites like Bleacher Report, and he is also the Editor-In-Chief of Agents Of Fandom. TJ has multiple 6-figure DFS wins in his career and most recently finished in 13th place at the 2022 FanDuel MLB Live Final. Follow TJ on Twitter – @TJ_Zwarych5