MLB Sleeper Fantasy Player Predictions for Friday (9/19)
Friday, September 19, 2025: Below are three of the best picks for today’s MLB slate on Sleeper Fantasy according to our projections team. Using factors like Statcast data, advanced sabermetrics, weather impacts, and environmental factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.
Don’t forget to check out our MLB weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks as the day progresses. And you can always stay up to date on exactly what a team’s lineup is by heading to our MLB starting lineups page.
Below, I’ll detail how I’m approaching things on Sleeper Fantasy for this Friday slate.
First… Sign Up to Make MLB Sleeper Fantasy Picks
If you want to play along but haven’t signed up yet, grab a special offer with our Sleeper Fantasy promo code “GRINDERS” to get a 100% deposit match up to $100! Sleeper Fantasy – one of the most popular DFS pick’em sites – provides player projections for MLB matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.
When making your MLB Sleeper picks today, let RotoGrinders do the heavy lifting for you!
Sleeper Fantasy Top MLB Picks for September 19, 2025
Now that you’re signed up, here are some of our top MLB DFS picks on Sleeper Fantasy for Friday:
- Clayton Kershaw less than 4.5 Pitcher Strikeouts
- Dylan Cease more than 3.5 Hits Allowed
- Trevor Rogers less than 5.5 Pitcher Strikeouts
Giants vs. Dodgers MLB Sleeper Fantasy Predictions
Clayton Kershaw less than 4.5 Pitcher Strikeouts
The pitcher strikeouts projection for Clayton Kershaw looks like a strong pick based on the current data. The Sleeper projection of 4.5 compares favorably based on our MLB simulations. This pick projects to hit 69.1% of the time based on the assumptions, and that represents a 6.2% edge.
Padres vs. White Sox MLB Sleeper Fantasy Predictions
Dylan Cease more than 3.5 Hits Allowed
The hits allowed projection for Dylan Cease looks like a strong pick based on the current data. The Sleeper projection of 3.5 compares favorably based on our MLB simulations. This pick projects to hit 69.0% of the time based on the assumptions, and that represents a 5.7% edge.
Yankees vs. Orioles MLB Sleeper Fantasy Predictions
Trevor Rogers less than 5.5 Pitcher Strikeouts
The pitcher strikeouts projection for Trevor Rogers looks like a strong pick based on the current data. The Sleeper projection of 5.5 compares favorably based on our MLB simulations. This pick projects to hit 63.8% of the time based on the assumptions, and that represents a 4.6% edge.
Editor’s Note: Looking for more places to play? Check out our Underdog promo code and PrizePicks promo code.
Image Credit: Imagn