MLB Sleeper Fantasy Player Predictions for Tuesday (9/16)
Tuesday, September 16, 2025: Below are three of the best picks for today’s MLB slate on Sleeper Fantasy according to our projections team. Using factors like Statcast data, advanced sabermetrics, weather impacts, and environmental factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.
Don’t forget to check out our MLB weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks as the day progresses. And you can always stay up to date on exactly what a team’s lineup is by heading to our MLB starting lineups page.
Below, I’ll detail how I’m approaching things on Sleeper Fantasy for this Tuesday slate.
First… Sign Up to Make MLB Sleeper Fantasy Picks
If you want to play along but haven’t signed up yet, grab a special offer with our Sleeper Fantasy promo code “GRINDERS” to get a 100% deposit match up to $100! Sleeper Fantasy – one of the most popular DFS pick’em sites – provides player projections for MLB matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.
When making your MLB Sleeper picks today, let RotoGrinders do the heavy lifting for you!
Sleeper Fantasy Top MLB Picks for September 16, 2025
Now that you’re signed up, here are some of our top MLB DFS picks on Sleeper Fantasy for Tuesday:
- Joey Cantillo more than 5.5 Pitcher Strikeouts
- Cal Raleigh less than 0.5 Walks
- Jeffrey Springs more than 5.5 Hits Allowed
Guardians vs. Tigers MLB Sleeper Fantasy Predictions
Joey Cantillo more than 5.5 Pitcher Strikeouts
The pitcher strikeouts projection for Joey Cantillo looks like a strong pick based on the current data. The Sleeper projection of 5.5 compares favorably based on our MLB simulations. This pick projects to hit 55.2% of the time based on the assumptions, and that represents a 6.4% edge.
Mariners vs. Royals MLB Sleeper Fantasy Predictions
Cal Raleigh less than 0.5 Walks
The walks projection for Cal Raleigh looks like a strong pick based on the current data. The Sleeper projection of 0.5 compares favorably based on our MLB simulations. This pick projects to hit 62.9% of the time based on the assumptions, and that represents a 6.1% edge.
Athletics vs. Red Sox MLB Sleeper Fantasy Predictions
Jeffrey Springs more than 5.5 Hits Allowed
The hits allowed projection for Jeffrey Springs looks like a strong pick based on the current data. The Sleeper projection of 5.5 compares favorably based on our MLB simulations. This pick projects to hit 57.9% of the time based on the assumptions, and that represents a 5.6% edge.
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