NBA Sleeper Fantasy Player Predictions for Tuesday (10/21)
Tuesday, October 21, 2025: Below are three of the best picks for today’s NBA slate on Sleeper Fantasy according to our projections team. Using factors like advanced analytics, minutes, matchups, and pace, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.
Keep in mind that the NBA news cycle can get crazy, so what is listed below may become a better/worse play depending on how news breaks. Be sure to keep close tabs on our NBA starting lineups page and NBA injury report to get a current snapshot of who is in/out and what a team’s rotation and depth chart looks like.
Below, I’ll detail how I’m approaching things on Sleeper Fantasy for this Tuesday slate.
First… Sign Up to Make NBA Sleeper Fantasy Picks
If you want to play along but haven’t signed up yet, grab a special offer with our Sleeper Fantasy promo code “GRINDERS” to unlock a generous bonus. Sleeper Fantasy – one of the most popular DFS pick’em sites – provides player projections for NBA matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.
When making your NBA Sleeper picks today, let RotoGrinders do the heavy lifting for you!
Sleeper Fantasy Top NBA Picks for October 21, 2025
Now that you’re signed up, here are some of our top NBA DFS picks on Sleeper Fantasy for Tuesday:
- Alex Caruso less than 2.5 Rebounds
- Deandre Ayton less than 24.5 Points & Rebounds
Rockets vs. Thunder NBA Sleeper Fantasy Predictions
Alex Caruso less than 2.5 Rebounds
The rebounds projection for Alex Caruso looks like a strong pick based on the current data. The Sleeper projection of 2.5 compares favorably based on our NBA simulations. This pick projects to hit 55.6% of the time based on the assumptions, and that represents a 7.7% edge.
Warriors vs. Lakers NBA Sleeper Fantasy Predictions
Deandre Ayton less than 24.5 Points & Rebounds
The points & rebounds projection for Deandre Ayton looks like a strong pick based on the current data. The Sleeper projection of 24.5 compares favorably based on our NBA simulations. This pick projects to hit 59.2% of the time based on the assumptions, and that represents a 3.6% edge.
Editor’s Note: Looking for more places to play? Check out our Underdog promo code and PrizePicks promo code.
Image Credit: Imagn