NFL DFS Pick Six Show: Week 10
Dean Shavelson from RotoGrinders is joined by John Daigle and Rich Hribar (aka LordReebs) to break down their top three games for the Week 10 NFL slate. They also share some favorite picks at each skill position, helping you prepare for the week ahead!
Show Highlights
The Pick Six crew breaks down the best three NFL games to target in DFS for Week 10, with additional insights into core strategy, player pools, and injury notes.
Watch the video below to hear all about Week 10’s NFL DFS slate!
Three Key Games to Target
Baltimore Ravens at Minnesota Vikings
- Lamar Jackson is spotlighted as a ceiling play facing a blitz-heavy Minnesota defense; Zay Flowers is his prime stack partner, but tepid touchdown equity tempers expectations.
- The Vikings offense is more uncertain— J.J. McCarthy is largely unproven, and Justin Jefferson’s DFS utility remains muted unless the game provides unexpected back-and-forth scoring.
Chicago Bears vs. New York Giants
- Both teams are attacked more in the run game; plug-and-play running backs, especially if injuries open up value, are highlighted.
- Rome Odunze is called out as a potential “bounce-back” wide receiver, with strong man-coverage metrics and a favorable matchup.
Los Angeles Rams vs. San Francisco 49ers
- Matthew Stafford and the Rams’ passing attack stand out against a pressure-starved Niners defense.
- Christian McCaffrey is viewed as the clear payoff RB, with heavy usage expected even in negative game scripts.
- Value receiving options like Jauan Jennings and Puka Nacua are featured for their affordable prices and target volume.

