NFL PrizePicks Player Predictions for Week 6
Week 6: Below are three of the best picks for this week’s NFL slate on PrizePicks according to our projections team. Using factors like advanced participation data, the latest efficiency analytics, historical trends, and advanced matchup factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.
Don’t forget to check out our NFL weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks as the week progresses. And you can always stay up to date on exactly what a team’s depth chart is looking like by heading to our NFL starting lineups page.
Below, I’ll detail how I’m approaching things on PrizePicks for Week 6.
First… Sign Up to Make NFL PrizePicks Picks
If you want to play along but haven’t signed up yet, grab a special offer with our PrizePicks promo code “GRINDERS” to get $50 on a $5 entry! PrizePicks – one of the most popular DFS pick’em sites – provides player projections for NFL matchups each week. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.
When making your NFL PrizePicks picks today, let RotoGrinders do the heavy lifting for you!
PrizePicks Top NFL Picks for Week 6
Now that you’re signed up, here are some of our top NFL DFS picks on PrizePicks for Week 6:
- Josh Jacobs less than 2.5 Receptions
- Daniel Jones more than 16.5 Rushing Yards
- Jacory Croskey-Merritt less than 63.5 Rushing Yards

Bengals vs. Packers NFL PrizePicks Predictions
Josh Jacobs less than 2.5 Receptions
The receptions projection for Josh Jacobs looks like a strong pick based on the current data. The PrizePicks projection of 2.5 compares favorably based on our NFL simulations. This pick projects to hit 61.5% of the time based on the assumptions, and that represents a 7.1% edge.
Cardinals vs. Colts NFL PrizePicks Predictions
Daniel Jones more than 16.5 Rushing Yards
The rushing yards projection for Daniel Jones looks like a strong pick based on the current data. The PrizePicks projection of 16.5 compares favorably based on our NFL simulations. This pick projects to hit 60.8% of the time based on the assumptions, and that represents a 6.5% edge.
Bears vs. Commanders NFL PrizePicks Predictions
Jacory Croskey-Merritt less than 63.5 Rushing Yards
The rushing yards projection for Jacory Croskey-Merritt looks like a strong pick based on the current data. The PrizePicks projection of 63.5 compares favorably based on our NFL simulations. This pick projects to hit 60.2% of the time based on the assumptions, and that represents a 5.9% edge.
Editor’s Note: Looking for more places to play? Check out our Underdog promo code and Sleeper promo code.
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