MLB Player Props for Friday, 9/25: Best Bets & Predictions Today

What kind of performances can we expect from Elly De La Cruz, Jake Bauers, and Wade Meckler? Follow along as our MLB betting analyst, Nick Galaida, breaks down three of his favorite MLB prop bets for Friday, September 25, 2026. Get all of Nick’s props, including picks from other experts as well as access to PickLabs, by subscribing to the RG Props package.
Major League Baseball has 15 evening games on tap for Friday, beginning with the second game of a doubleheader between the Cubs and Red Sox at Fenway Park.
There is severe MLB weather across the league today, including extreme wind in Boston, Philadelphia, and New York. As always, be mindful of the forecast before making any wagers!
Below, you can find three of my favorite picks for Friday, September 25th!
Best MLB Player Props for Friday, September 25th
Here are my top player prop bets for today, with the first pitch scheduled for 5:30 PM ET on Friday, September 25th:
- Elly De La Cruz Over/Under 1.5 Hits + Runs + RBIs
- Jake Bauers Over/Under 1.5 Hits + Runs + RBIs
- Wade Meckler Over/Under 1.5 Hits + Runs + RBIs
Elly De La Cruz OVER 1.5 Hits + Runs + RBIs (-110, BetMGM)
Jose Soriano has struggled to a 5.37 FIP across the platoon during the last 30 days. He’s only struck out 10.5% of the left-handed hitters he has faced during that stretch, indicating a clear inability to fool hitters.
De La Cruz has a 129 wRC+ against right-handed pitching in 2026 and has been scorching hot in September, with a .377 batting average and 233 wRC+.
Jake Bauers OVER 1.5 Hits + Runs + RBIs (+100, BetMGM)
Michael McGreevy has struggled to a 5.24 FIP and 1.71 WHIP across the platoon during the last 30 days. Bauers has been extremely productive against right-handed pitching this season, hitting .266 with a 142 wRC+. Bauers has been seeing the ball well of late, with a 145 wRC+ across his last 43 plate appearances. This is good value for a player who should be in the top half of the Milwaukee lineup on Friday.
Wade Meckler OVER 1.5 Hits + Runs + RBIs (+116, DraftKings)
During the last 30 days, Bryce Miller has struggled to a 5.09 FIP and 1.50 WHIP across the platoon. His 9.3% swinging-strike rate and 89.1% in-zone contact rate allowed are both signs that he’s not fooling many hitters right now.
Meckler has a .310 batting average and 127 wRC+ against right-handed pitching this year. This is good value for a hitter in a good matchup, who should be in the 3-hole of the Angels lineup.
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