MLB Player Props for Wednesday, 5/6: Best Bets & Predictions Today
What kind of performances can we expect from Tyler Glasnow, Brandon Young, and Zack Wheeler? Follow along as our MLB betting analyst, Nick Galaida, breaks down three of his favorite MLB prop bets for Wednesday, May 6, 2026. Get all of Nick’s picks, including more MLB plays, by subscribing to the RotoGrinders Props & Pick’em package.
Wednesday’s 15-game MLB slate features 6 afternoon games, which should keep fans busy throughout the work day – maybe just not for reasons their company is expecting!
The MLB weather continues to laugh in the face of hitters. The temperature forecast at first pitch in Colorado is below 40 degrees. There are also cool temperatures forecast in Chicago, Kansas City, Detroit, and St. Louis. It could be another rough day for offense around the league.
Below, you can find three of my favorite picks for Wednesday, May 6th!
Best MLB Player Props for Wednesday, May 6th
Here are my top player prop bets for today, with the first pitch scheduled for 1:10 PM ET on Wednesday, May 6th:
- Tyler Glasnow Over/Under 2.5 Walks Allowed
- Brandon Young Over/Under 15.5 Outs Recorded
- Zack Wheeler Over/Under 6.5 Strikeouts
Tyler Glasnow UNDER 2.5 Walks Allowed (-189, DraftKings)
DRAFTKINGSThis line is a massive overreaction to Glasnow walking 6 batters against the Marlins in his most recent outing. All 6 batters Glasnow walked in that start were lefties. That was the first time this season that Glasnow had walked more than 2 batters in a single game.
This season, Glasnow has a 4% walk rate against righties, compared to an 11.7% walk rate across the platoon. He will see 5 righties against Houston. The math strongly supports the under.
Brandon Young OVER 15.5 Outs Recorded (+110, DraftKings)
DRAFTKINGSYoung completed only 4 innings against the Astros in his most recent start, but he still faced 25 batters. It’s not very often that a pitcher will surrender 10 runs or 9 hits in a baseball game, no matter how a person feels about their overall talent level.
The most important thing to consider here is that Baltimore’s arm barn is extremely taxed. Baltimore could desperately use some length from Young, even if that only means one additional out in the 6th inning. Young should be good for another 25 batters faced – that’s more than enough opportunity to bet the over here at plus money.
Zack Wheeler UNDER 6.5 Strikeouts (-106, DraftKings)
DRAFTKINGSWheeler has a 32.6% strikeout rate in 2 starts since being activated from the injured list, but there are reasons to anticipate some negative regression in that department sooner rather than later. Compared to last season, his velocity is down considerably – from 96.1 mph on his heater last season to 94.3 mph this season.
More breaking stuff has helped him rack up strikeouts this season, but teams will adjust. Wheeler’s sinker, which is the pitch he has used most frequently against righties, hasn’t generated a single swing-and-miss this season at the MLB level. Wheeler’s heavy 4-seam/splitter dependency across the platoon could get him into trouble if teams eventually stop chasing the splitter below the zone.
The Athletics have the 5th-highest swing% in baseball during the last 14 days, but they don’t chase bad pitches at an alarming rate. Wheeler is likely going to have to come into the zone to earn strikeouts, and it could be tough to get to 7 strikeouts in this matchup.
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