MLB PrizePicks Player Predictions for Monday (9/1)
Monday, September 1, 2025: Below are three of the best picks for today’s MLB slate on PrizePicks according to our projections team. Using factors like Statcast data, advanced sabermetrics, weather impacts, and environmental factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.
Don’t forget to check out our MLB weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks as the day progresses. And you can always stay up to date on exactly what a team’s lineup is by heading to our MLB starting lineups page.
Below, I’ll detail how I’m approaching things on PrizePicks for this Monday slate.
First… Sign Up to Make MLB PrizePicks Picks
If you want to play along but haven’t signed up yet, grab a special offer with our PrizePicks promo code “GRINDERS” to get $50 on a $5 entry! PrizePicks – one of the most popular DFS pick’em sites – provides player projections for MLB matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.
When making your PrizePicks picks today, let RotoGrinders do the heavy lifting for you!
PrizePicks Top MLB Picks for September 1, 2025
Now that you’re signed up, here are some of our top MLB DFS picks on PrizePicks for Monday:
- Parker Messick more than 15.5 Outs
- Brayan Bello less than 4.5 Pitcher Strikeouts
- Sean Manaea more than 5.5 Pitcher Strikeouts
PRIZEPICKSGuardians vs. Red Sox MLB PrizePicks Predictions
Parker Messick more than 15.5 Outs
The outs projection for Parker Messick looks like a strong pick based on the current data. The PrizePicks projection of 15.5 compares favorably based on our MLB simulations. This pick projects to hit 60.3% of the time based on the assumptions, and that represents a 5.9% edge.
Brayan Bello less than 4.5 Pitcher Strikeouts
The pitcher strikeouts projection for Brayan Bello looks like a strong pick based on the current data. The PrizePicks projection of 4.5 compares favorably based on our MLB simulations. This pick projects to hit 58.7% of the time based on the assumptions, and that represents a 4.3% edge.
Mets vs. Tigers MLB PrizePicks Predictions
Sean Manaea more than 5.5 Pitcher Strikeouts
The pitcher strikeouts projection for Sean Manaea looks like a strong pick based on the current data. The PrizePicks projection of 5.5 compares favorably based on our MLB simulations. This pick projects to hit 57.7% of the time based on the assumptions, and that represents a 3.4% edge.
Editor’s Note: Looking for more places to play? Check out our Underdog promo code and Sleeper promo code.
Image Credit: Imagn