MLB Sleeper Fantasy Player Predictions for Thursday (4/16)

Buehler of the Padres

Thursday, April 16, 2026: Below are three of the best picks for today’s MLB slate on Sleeper Fantasy according to our projections team. Using factors like Statcast data, advanced sabermetrics, weather impacts, and environmental factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.

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Don’t forget to check out our MLB weather page to see how that may impact these picks as the day progresses. And you can always stay up to date on exactly what a team’s lineup is by heading to our MLB starting lineups page.

Below, I’ll detail how I’m approaching things on Sleeper Fantasy for this Thursday slate.

First… Sign Up to Make MLB Sleeper Fantasy Picks

If you want to play along but haven’t signed up yet, grab a special offer with our Sleeper Fantasy promo code to unlock a generous bonus. Sleeper Fantasy – one of the most popular DFS pick’em sites – provides player projections for MLB matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.

When making your MLB Sleeper picks today, let RotoGrinders do the heavy lifting for you!

Sleeper Fantasy Top MLB Picks for April 16, 2026

Now that you’re signed up, here are some of our top MLB DFS picks on Sleeper Fantasy for Thursday:

Mariners vs. Padres MLB Sleeper Fantasy Predictions

Brendan Donovan more than 0.5 Walks

The walks projection for Brendan Donovan looks like a strong pick based on the current data. The Sleeper projection of 0.5 compares favorably based on our MLB simulations. This pick projects to hit 53.4% of the time based on the assumptions, and that represents a 9.0% edge.

Walker Buehler less than 3.5 Pitcher Strikeouts

The pitcher strikeouts projection for Walker Buehler looks like a strong pick based on the current data. The Sleeper projection of 3.5 compares favorably based on our MLB simulations. This pick projects to hit 64.4% of the time based on the assumptions, and that represents a 7.5% edge.

Rockies vs. Astros MLB Sleeper Fantasy Predictions

Edouard Julien more than 1.5 Hits + Runs + RBIs

The hits + runs + RBIs projection for Edouard Julien looks like a strong pick based on the current data. The Sleeper projection of 1.5 compares favorably based on our MLB simulations. This pick projects to hit 56.5% of the time based on the assumptions, and that represents a 6.3% edge.

Editor’s Note: Looking for more places to play? Check out our Underdog promo code and PrizePicks promo code.

Image Credit: Imagn

About the Author

meansy53
Andy Means (meansy53)

Andy Means (aka meansy53) was a walk-on with the esteemed Duke University basketball team for 3 years before graduating in 2004. He also has a Master’s in Accounting from the Indiana University Kelley School of Business and has been playing DFS since 2014 (qualifying for multiple Live Finals). In the summer of 2022, Andy took over the role of Premium Content Director for the RotoGrinders Network, overseeing the vast array of content that is created on RotoGrinders, ScoresAndOdds, and FantasyLabs. Follow Andy on X – @ameansy
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