MLB Sleeper Fantasy Player Predictions for Thursday (9/25)
Thursday, September 25, 2025: Below are three of the best picks for today’s MLB slate on Sleeper Fantasy according to our projections team. Using factors like Statcast data, advanced sabermetrics, weather impacts, and environmental factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.
Don’t forget to check out our MLB weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks as the day progresses. And you can always stay up to date on exactly what a team’s lineup is by heading to our MLB starting lineups page.
Below, I’ll detail how I’m approaching things on Sleeper Fantasy for this Thursday slate.
First… Sign Up to Make MLB Sleeper Fantasy Picks
If you want to play along but haven’t signed up yet, grab a special offer with our Sleeper Fantasy promo code “GRINDERS” to get a 100% deposit match up to $100! Sleeper Fantasy – one of the most popular DFS pick’em sites – provides player projections for MLB matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.
When making your MLB Sleeper picks today, let RotoGrinders do the heavy lifting for you!
Sleeper Fantasy Top MLB Picks for September 25, 2025
Now that you’re signed up, here are some of our top MLB DFS picks on Sleeper Fantasy for Thursday:
- Tyler Mahle less than 4.5 Pitcher Strikeouts
- Janson Junk more than 5.5 Hits Allowed
- Ildemaro Vargas less than 1.5 Hits + Runs + RBIs
Twins vs. Rangers MLB Sleeper Fantasy Predictions
Tyler Mahle less than 4.5 Pitcher Strikeouts
The pitcher strikeouts projection for Tyler Mahle looks like a strong pick based on the current data. The Sleeper projection of 4.5 compares favorably based on our MLB simulations. This pick projects to hit 55.1% of the time based on the assumptions, and that represents a 5.6% edge.
Marlins vs. Phillies MLB Sleeper Fantasy Predictions
Janson Junk more than 5.5 Hits Allowed
The hits allowed projection for Janson Junk looks like a strong pick based on the current data. The Sleeper projection of 5.5 compares favorably based on our MLB simulations. This pick projects to hit 66.2% of the time based on the assumptions, and that represents a 4.9% edge.
Dodgers vs. Diamondbacks MLB Sleeper Fantasy Predictions
Ildemaro Vargas less than 1.5 Hits + Runs + RBIs
The hits + runs + RBIs projection for Ildemaro Vargas looks like a strong pick based on the current data. The Sleeper projection of 1.5 compares favorably based on our MLB simulations. This pick projects to hit 66.2% of the time based on the assumptions, and that represents a 4.1% edge.
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Image Credit: Imagn