MLB Underdog Fantasy Player Predictions for Friday (9/26)
Friday, September 26, 2025: Below are three of the best picks for today’s MLB slate on Underdog Fantasy according to our projections team. Using factors like Statcast data, advanced sabermetrics, weather impacts, and environmental factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.
Don’t forget to check out our MLB weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks as the day progresses. And you can always stay up to date on exactly what a team’s lineup is by heading to our MLB starting lineups page.
Below, I’ll detail how I’m approaching things on Underdog for this Friday slate.
First… Sign Up to Make MLB Underdog Fantasy Picks
If you want to play along but haven’t signed up yet, grab a special offer with our Underdog Fantasy promo code “GRINDERS” to unlock up to $1,000 Bonus Cash courtesy of a generous deposit match. Underdog Fantasy – one of the most popular DFS pick’em sites – provides player projections for MLB matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.
When making your MLB Underdog picks today, let RotoGrinders do the heavy lifting for you!
Underdog Fantasy Top MLB Picks for September 26, 2025
Now that you’re signed up, here are some of our top MLB DFS picks on Underdog for Friday:
- Zack Littell higher than 4.5 Hits Allowed
- Emmet Sheehan higher than 5.5 Pitcher Strikeouts
- Joe Ryan higher than 15.5 Outs
Reds vs. Brewers MLB Underdog Predictions
Zack Littell higher than 4.5 Hits Allowed
The hits allowed projection for Zack Littell looks like a strong pick based on the current data. The Underdog projection of 4.5 compares favorably based on our MLB simulations. This pick projects to hit 70.2% of the time based on the assumptions, and that represents a 1.4% edge.
Dodgers vs. Mariners MLB Underdog Predictions
Emmet Sheehan higher than 5.5 Pitcher Strikeouts
The strikeouts projection for Emmet Sheehan looks like a strong pick based on the current data. The Underdog projection of 5.5 compares favorably based on our MLB simulations. This pick projects to hit 69.2% of the time based on the assumptions, and that represents a 1.1% edge.
Twins vs. Phillies MLB Underdog Predictions
Joe Ryan higher than 15.5 Outs
The outs projection for Joe Ryan looks like a strong pick based on the current data. The Underdog projection of 15.5 compares favorably based on our MLB simulations. This pick projects to hit 55.1% of the time based on the assumptions, and that represents a 1.1% edge.
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