Monday Night Football Betting Picks: Seahawks at 49ers

MNF-Wk10

NFL Week 10 concludes with an exciting Monday Night Football matchup between MVP front runner Russell Wilson and rising star, Jimmy Garoppolo. The San Francisco 49ers are 6.5-point favorites and the total has moved from 45 to 47.5 with more than 80% of bets on the Over at online sports betting sites.

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Monday Night Football Betting Picks — Seattle Seahawks at San Francisco 49ers

Spread: San Francisco 49ers -6.5 (use our FanDuel Sportsbook promo code to get these odds)

60% of bets are on Seahawks (+6/6.5) per VegasInsider.com.

Over/Under: 47.5

86% of bets are on the Over

Lucky for NFL fans, Week 10 of Monday Night Football will not follow the theme of lackluster matchups that has been consistent throughout the NFL season. This week, the undefeated San Francisco 49ers host MVP favorite Russell Wilson and the Seattle Seahawks. While the 49ers are favored by nearly a touchdown at home, bettors expect a close game with 60% of bets backing the Seahawks.

Injuries in the Bay

The 49ers have gotten this far without losing a game, in large part, thanks to one of the best defenses in the league led by a ferocious pass rush that is sacking quarterbacks on 11.32% of dropbacks. A key component to the defensive unit’s success has been Kwon Alexander, who the 49ers will be without for the first time all season after Alexander suffered a pectoral injury against the Arizona Cardinals. Alexander accounted for 34 tackles, 3.5 tackles for loss, and two forced turnovers through eight games.

Most notably, San Francisco’s offense will likely be without Pro Bowl tight end George Kittle on Monday. Kittle is listed as doubtful with unspecified injuries to his leg. If Kittle does, in fact, sit this one out, second-year tight end Ross Dwelley will be called upon to take his place. Dwelley makes a good DFS play in Showdown contests Monday night.

For more injury news, check out DFS analyst Justin Van Zuiden’s (stlcardinals84) breakdown in RotoGrinders’ weekly NFL Grind Down series.

My Monday Night Football Betting Picks – Seahawks at 49ers

The 49ers haven’t tripped up yet, but injuries to both the offense and defense will make it tough for the 49ers to cover the spread Monday night. I think the loss of Alexander is going way underlooked. Additionally, the Seahawks will be adding pieces to a roster that has already won seven of their first nine games. On Sunday, Pete Carroll said Josh Gordon, who was picked up on waivers less than two weeks ago, had a “good chance of playing” and that defensive back Quandre Diggs was ready to go.

Not only will I take the Seahawks +6.5, but I’ll also take the Under. As stated earlier, the line has moved 2.5 points, from 45 to 47.5. The absence of Alexander does lead me to believe the Seahawks will have more opportunities to put up points, but both teams are near the bottom in terms of pace; the 49ers are 27th and the Seahawks are 21st. With Kittle likely sidelined, the Seahawks will be able to devote more attention to stopping Emmanuel Sanders and the running game, not to mention the presence of Quandre Diggs certainly won’t hurt.

My MNF Betting Picks: Seahawks +6.5; Under 47.5

Monday Night Football Betting Picks — Player Props

Emmanuel Sanders Over 65.5 Receiving yards (-112)

Sanders Over 4.5 Receptions (-142) at FanDuel

Sanders 9+ receptions (+850) at PointsBet

As I touch on in Week 10 NFL Monday Night Football prop bets and picks over at NJ.com, I really like the way this sets up for Emmanuel Sanders. Sanders will be Garoppolo’s no. 1 target if Kittle sits out. I also don’t think it’s too far fetched for the Seahawks to be leading this game, which would force more passes on behalf of Kyle Shanahan’s somewhat run-heavy offense. Moreover, the Seahawks secondary has been an easy target through the air. Mike Evans most recently went for 12 receptions and 180 yards. Prior to that, Julio Jones put up 10-152 stat line, and Odell (player-popup #odell-beckham)Beckham Jr went for 6-101.

Monday Night Football NFL Betting Picks – First Touchdown

Ross Dwelley +1900 – Use our PointsBet promo code to get these odds.

Emmanuel Sanders +850 – Use our DraftKings Sportsbook promo code to get these odds.

DK Metcalf +1200 (FD)

Russell Wilson +3500 (DK)

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Monkey Knife Fight Player Props

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Here are my favorite Monkey Knife Fight picks for Monday Night Football:

Touchdown Dance (1.5x): Emmanuel Sanders + Tevin Coleman + Tyler Lockett OVER 1.5 touchdowns

My MNF Betting Card

Image Credit: USA Today Sports Images

About the Author

schmitto
Matt Schmitto (schmitto)

Matt Schmitto is an Organic Strategy Lead for Better Collective. He was introduced to daily fantasy sports in 2012 and soon became a member at RotoGrinders. Seven years later, Schmitto joined RotoGrinders Network full time as a staff writer shortly after the Supreme Court overturned PASPA. He has since covered important stories in the sports betting and fantasy sports industries for sites like SportsHandle and USBets and has had roles as a sports betting editor and commercial content lead. He continues to play DFS and loves placing Futures bets at sportsbooks. His favorite DFS sites are Underdog Fantasy, and PrizePicks, and DraftKings. Follow Schmitto on Twitter – @Matt_Schmitto