NFL Sleeper Fantasy Player Predictions for Panthers vs. 49ers MNF (11/24)
Week 12, Monday Night Football: Below are three of the best picks on Sleeper Fantasy according to our projections team for the Panthers vs. 49ers game on November 24, 2025. Using factors like advanced participation data, the latest efficiency analytics, historical trends, and advanced matchup factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.
Don’t forget to check out our NFL weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks. And you can always stay up to date on exactly what a team’s depth chart is looking like by heading to our NFL starting lineups page.
Below, I’ll detail how I’m approaching things on Sleeper Fantasy for Panthers vs. 49ers.
First… Sign Up to Make NFL Sleeper Fantasy Picks
If you want to play along but haven’t signed up yet, grab a special offer with our Sleeper Fantasy promo code “GRINDERS” to unlock a generous bonus. Sleeper Fantasy – one of the most popular DFS pick’em sites – provides player projections for NFL matchups each week. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.
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Sleeper Fantasy Top NFL Picks for Panthers vs. 49ers
Now that you’re signed up, here are some of our top NFL DFS picks on Sleeper Fantasy for Monday Night Football:
- George Kittle less than 4.5 Receptions
- Bryce Young more than 33.5 Passing Attempts
- Brock Purdy less than 31.5 Passing Attempts
Panthers vs. 49ers NFL Sleeper Fantasy Predictions
George Kittle less than 4.5 Receptions
The receptions projection for George Kittle looks like a strong pick based on the current data. The Sleeper projection of 4.5 compares favorably based on our NFL simulations. This pick projects to hit 53.1% of the time based on the assumptions, and that represents a 3.1% edge.
Bryce Young more than 33.5 Passing Attempts
The passing attempts projection for Bryce Young looks like a strong pick based on the current data. The Sleeper projection of 33.5 compares favorably based on our NFL simulations. This pick projects to hit 48.4% of the time based on the assumptions, and that represents a 2.4% edge.
Brock Purdy less than 31.5 Passing Attempts
The passing attempts projection for Brock Purdy looks like a strong pick based on the current data. The Sleeper projection of 31.5 compares favorably based on our NFL simulations. This pick projects to hit 56.6% of the time based on the assumptions, and that represents a 1.6% edge.
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