MLB Underdog Fantasy Player Predictions for Wednesday (6/25)

Ryan of the Twins

Wednesday, June 25, 2025: Below are three of the best picks for today’s MLB slate on Underdog Fantasy according to our projections team. Using factors like Statcast data, advanced sabermetrics, weather impacts, and environmental factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.

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Don’t forget to check out our MLB weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks as the day progresses. And you can always stay up to date on exactly what a team’s lineup is by heading to our MLB starting lineups page.

Below, I’ll detail how I’m approaching things on Underdog for this Wednesday slate.

First… Sign Up to Make MLB Underdog Fantasy Picks

If you want to play along but haven’t signed up yet, grab a special offer with our Underdog Fantasy promo code “GRINDERS” to unlock up to $1,000 Bonus Cash courtesy of a generous deposit match. Underdog Fantasy – one of the most popular DFS pick’em sites – provides player projections for MLB matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.

When making your Underdog picks today, let RotoGrinders do the heavy lifting for you!

Underdog Fantasy Top MLB Picks for June 25, 2025

Now that you’re signed up, here are some of our top MLB DFS picks on Underdog for Wednesday:

Cubs vs. Cardinals MLB Underdog Predictions

Erick Fedde lower than 17.5 Outs

The outs projection for Erick Fedde looks like a strong pick based on the current data. The Underdog projection of 17.5 compares favorably based on our MLB simulations. This pick projects to hit 61.9% of the time based on the assumptions, and that represents a 4.1% edge.

Athletics vs. Tigers MLB Underdog Predictions

Jacob Lopez higher than 4.5 Pitcher Strikeouts

The pitcher strikeouts projection for Jacob Lopez looks like a strong pick based on the current data. The Underdog projection of 4.5 compares favorably based on our MLB simulations. This pick projects to hit 73.6% of the time based on the assumptions, and that represents a 4.0% edge.

Mariners vs. Twins MLB Underdog Predictions

Joe Ryan lower than 6.5 Pitcher Strikeouts

The pitcher strikeouts projection for Joe Ryan looks like a strong pick based on the current data. The Underdog projection of 6.5 compares favorably based on our MLB simulations. This pick projects to hit 54.1% of the time based on the assumptions, and that represents a 2.9% edge.

Editor’s Note: Looking for more places to play? Check out our PrizePicks promo code and Sleeper promo code.

Image Credit: Imagn

About the Author

Jbails26
Justin Bailey (Jbails26)

Justin Bailey (aka jbails26) is the Lead Editor for RotoGrinders and FantasyLabs. He’s been playing DFS since 2013 and specializes in small-field NFL and PGA contests (but still dabbles in MME). Justin qualified for the DraftKings Fantasy Golf World Championship in 2023. Follow Justin on Twitter – @justinbailey32