MLB Underdog Fantasy Player Predictions for Wednesday (5/28)

Cameron of the Royals

Wednesday, May 28, 2025: Below are three of the best picks for today’s MLB slate on Underdog Fantasy according to our projections team. Using factors like Statcast data, advanced sabermetrics, weather impacts, and environmental factors, every single pick is going to be based on what our projections say is a meaningful edge. Get access to all of these picks, including much more, by subscribing to the RotoGrinders Props & Pick’em package.

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Don’t forget to check out our MLB weather page, which is curated by our Chief Meteorologist, Kevin Roth, to see how that may impact these picks as the day progresses. And you can always stay up to date on exactly what a team’s lineup is by heading to our MLB starting lineups page.

We have 15 games on the MLB schedule for today. Below, I’ll detail how I’m approaching things on Underdog for this Wednesday slate.

First… Sign Up to Make MLB Underdog Fantasy Picks

If you want to play along but haven’t signed up yet, grab a special offer with our Underdog Fantasy promo code “GRINDERS” to unlock up to $1,000 Bonus Cash courtesy of a generous deposit match. Underdog Fantasy – one of the most popular DFS pick’em sites – provides player projections for MLB matchups each day. It is then up to the user to decide whether a player will ultimately exceed or fall short of those projections in the games. With a huge roster of players available from which to choose, we just need to make a minimum of two picks to build an entry.

When making your Underdog picks today, let RotoGrinders do the heavy lifting for you!

Underdog Fantasy Top MLB Picks for May 28, 2025

Now that you’re signed up, here are some of our top MLB DFS picks on Underdog for Wednesday:

Reds vs. Royals MLB Underdog Fantasy Predictions

Here are the Reds vs. Royals MLB Underdog Fantasy predictions for tonight:

Noah Cameron lower than 4.5 Pitcher Strikeouts

The strikeouts projection for Noah Cameron looks like a strong pick based on the current data. The Underdog projection of 4.5 compares favorably based on our MLB simulations. This pick projects to hit 60.4% of the time based on the assumptions, and that represents a 2.6% edge.

Blue Jays vs. Rangers MLB Underdog Fantasy Predictions

Here are the Blue Jays vs. Rangers MLB Underdog Fantasy predictions for tonight:

Tyler Mahle lower than 4.5 Pitcher Strikeouts

The strikeouts projection for Tyler Mahle looks like a strong pick based on the current data. The Underdog projection of 4.5 compares favorably based on our MLB simulations. This pick projects to hit 68.3% of the time based on the assumptions, and that represents a 2.6% edge.

Nationals vs. Mariners MLB Underdog Fantasy Predictions

Here are the Nationals vs. Mariners MLB Underdog Fantasy predictions for tonight:

George Kirby lower than 5.5 Pitcher Strikeouts

The strikeouts projection for George Kirby looks like a strong pick based on the current data. The Underdog projection of 5.5 compares favorably based on our MLB simulations. This pick projects to hit 58.9% of the time based on the assumptions, and that represents a 1.1% edge.

Editor’s Note: Looking for more places to play? Check out our PrizePicks promo code and Sleeper promo code.

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About the Author

meansy53
Andy Means (meansy53)

Andy Means (aka meansy53) was a walk-on with the esteemed Duke University basketball team for 3 years before graduating in 2004. He also has a Master’s in Accounting from the Indiana University Kelley School of Business and has been playing DFS since 2014. He has qualified for multiple Live Finals and displays his extensive basketball knowledge as a host of our top show – NBA Crunch Time. In the summer of 2022, Andy took over the role of Premium Content Director for the RotoGrinders Network, overseeing the vast array of content that is created on RotoGrinders, ScoresAndOdds, and FantasyLabs. Follow Andy on Twitter – @ameansy
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