NFL PrizePicks Top Plays: 49ers vs. Seahawks Player Predictions for Thursday Night Football
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Happy Thanksgiving to all who celebrate! Being here in Canada, it’ll be a few days heavy on content and light on turkey for me. However, I’m thankful that’s the case, as there are some really exciting games from an NFL DFS perspective on the Thanksgiving slate. This is definitely the case on PrizePicks, as there are a plethora of great spots for us to profit while spending some time with family.
Each week, I’ll deliver my top NFL PrizePicks predictions for Thursday, Sunday, and Monday Night Football. Use the PrizePicks referral code GRINDERS to receive a $100 deposit match to prep you for the NFL season.
PrizePicks Plays: 49ers vs. Seahawks
- Christian McCaffrey – More Than 0.5 Rushing Touchdowns
- Zach Charbonnet – More Than 18.5 Receiving Yards
- Brandon Aiyuk + DK Metcalf – More Than 0.5 Touchdowns (Combo)
Christian McCaffrey – 0.5 Rushing Touchdowns
Although he only tied the record for consecutive games with a touchdown, McCaffrey scoring is still almost always a foregone conclusion. The only question is whether or not it’ll be a receiving or rushing score. Christian McCaffrey not only has the highest rushing touchdown projection for Thanksgiving but the entire slate of Week 12 players. He has 9 rushing touchdowns through 10 games this year, and the 49ers are currently full touchdown favorites over the Seahawks, a team dealing with injuries. With a high projection and great potential game script, Christian McCaffrey to score a rushing touchdown on PrizePicks is simply too good to pass up.
Play: McCaffrey – More Than 0.5 Rushing Touchdowns
Zach Charbonnet – 18.5 Receiving Yards
The Seahawks are expected to be without Kenneth Walker for this one, so Zach Charbonnet should step into a pretty major role. He was already creeping in on Kenneth Walker’s touches recently and has had double-digit receiving yards in 4 of his last 5 games. Now without Walker, it should be very easy for Charbonnet to rack up catches in a bigger role against this tough 49ers pass rush. They’re likely to be trailing, and the 49ers are now likely the best pass rush in all of football, so Charbonnet should have to be an outlet for Geno Smith and get many quick passes. He currently projects for nearly 22 receiving yards in the RotoGrinders projections, and the more the 49ers get ahead, the better the chance Charbonnet surpasses his NFL PrizePicks total.
Play: Charbonnet – More Than 18.5 Receiving Yards
Brandon Aiyuk + DK Metcalf – 0.5 Touchdowns (Combo)
While I expect the 49ers to run away with this game, it’s entirely possible it will happen because Brandon Aiyuk has another monster game. With Brock Purdy back healthy, he has now scored a touchdown in back-to-back games and has received at least 6 targets in all but one game this entire season. He’s been an absolute monster and has a 0.42 touchdown projection at RotoGrinders. Thankfully we don’t have to rely fully on the 49ers receiver. The beauty of a combo DFS Pick’em prediction is how we have a chance regardless of the game script. If the likely scenario of the 49ers playing with the lead occurs, it could be a big night for DK Metcalf in garbage time. While the matchup against the 49ers isn’t great, there isn’t anyone in football who can physically go head-to-head with DK Metcalf regardless. The combination of Metcalf and Aiyuk should produce at least one trip to the end zone on Thanksgiving.