NFL DFS Week 10 Preview: Odds, Projections & Top DraftKings Picks

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Welcome to our NFL Week 10 Preview, where we delve into the exciting world of NFL DFS on platforms such as DraftKings. Whether you’re seeking NFL betting odds, DFS projections for the optimizer, projected ownership, or DFS picks for this week’s slate, this article has what you need. Join us as we do our NFL DFS research and review the landscape of the upcoming slate.

Week 10 NFL Odds

Team Opponent Spread Total Moneyline
Pittsburgh Steelerslogo Green Bay Packers logo -3 38.5 -180
Green Bay Packerslogo Pittsburgh Steelers logo 3 38.5 152
Baltimore Ravenslogo Cleveland Browns logo -6.5 38.5 -290
Cleveland Brownslogo Baltimore Ravens logo 6.5 38.5 235
Cincinnati Bengalslogo Houston Texans logo -6.5 46.5 -280
Houston Texanslogo Cincinnati Bengals logo 6.5 46.5 230
Tampa Bay Buccaneerslogo Tennessee Titans logo -1.5 38.5 -118
Tennessee Titanslogo Tampa Bay Buccaneers logo 1.5 38.5 -100
Minnesota Vikingslogo New Orleans Saints logo 3 40.5 126
New Orleans Saintslogo Minnesota Vikings logo -3 40.5 -148
Jacksonville Jaguarslogo San Francisco 49ers logo 3 45.5 140
San Francisco 49erslogo Jacksonville Jaguars logo -3 45.5 -166
Los Angeles Chargerslogo Detroit Lions logo 3 48.5 128
Detroit Lionslogo Los Angeles Chargers logo -3 48.5 -152
Arizona Cardinalslogo Atlanta Falcons logo 1.5 43.5 102
Atlanta Falconslogo Arizona Cardinals logo -1.5 43.5 -120
Seattle Seahawkslogo Washington Commanders logo -6.5 44.5 -300
Washington Commanderslogo Seattle Seahawks logo 6.5 44.5 245
Dallas Cowboyslogo New York Giants logo -17.5 39.5 -2200
New York Giantslogo Dallas Cowboys logo 17.5 39.5 1100

Odds courtesy of ScoresAndOdds betting data as of publication time.

NFL DFS DraftKings Projections

Player Projection Team Position
Joe Burrow 22.07 CIN QB
Christian McCaffrey 20.94 SFO RB
Ja’Marr Chase 21.48 CIN WR
T.J. Hockenson 15.22 MIN TE
Dallas Cowboys 10.48 DAL DST

Note: NFL DFS Projections are updated in real time and subject to change. Subscribe to RotoGrinders Premium and check out our Free Discord to get the most updated data and information prior to lock.

DraftKings Ownership Projections

Player pOwn%
Rachaad White 26.80
Tank Dell 23.53
Marquise Brown 21.24

Note: Ownership Projections are updated in real time and subject to change. Subscribe to RotoGrinders Premium and check out our Free Discord to get the most updated data and information prior to lock.

PrizePicks, Underdog, and Fantasy Pick’em Projections

Player Stat Projection
Jared Goff Passing Yards 278.65
Joe Mixon Rushing Yards 73.47
Ja’Marr Chase Receiving Yards 95.13
Amon-Ra St. Brown Receptions 7.65
Joe Burrow Fantasy Score 20.64

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Top NFL DFS Simulation Plays

Player Position Smash%
Joe Burrow Quarterback 20.71
Christian McCaffrey Running Back 26.31
Ja’Marr Chase Wide Receiver 24.63
Evan Engram Tight End 20.73
Dallas Cowboys Defense 10.59

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NFL DFS Pick’em Sites & Promo Offers for This Week:

Top NFL DFS Picks for Week 10

Christian McCaffrey continues to pace the field as the NFL’s top fantasy running back. Fresh off the bye, we should expect another solid week of production despite a tough matchup here in what should be a competitive game against the Jaguars.

Ja’Marr Chase got a bit banged up last week in the Bengals’ win against the Bills on Sunday Night, but with Tee Higgins not expected to play, if Chase is out there come Sunday, he should be in line for a massive workload in a Bengals offense that has Joe Burrow getting healthier from that lingering calf issue.

Marquise Brown should get a nice boost this week with Kyler Murray set to make his return to the lineup. Brown was already working in a nice role with a solid target share in this offense, but now with Murray back, his upside rises here.

Image Credit: Getty Images

About the Author

kmurray03
Kyle Murray (kmurray03)

While finishing up his college degree, Kyle Murray (aka kmurray03) became a full-time DFS player in 2018 after he won the first FanDuel FantaSea Live Final event for a $250,000 score. He has appeared in 6 Live Finals, qualifying for 10 total seats in that time, and has accumulated multiple 6-figure scores across several sports. In recent years, he has also added a focus towards prop betting, where he has turned a profit in multiple sports, such as NBA, MLB, and PGA. You can find all of Kyle’s sports betting analysis on our sister site, ScoresAndOdds. Follow Kyle on Twitter – @KMurrDFS