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MLB DFS First Look on DraftKings and FanDuel: Monday, September 22nd

by Derek Farnsworth (Notorious) Last Updated 2025-09-22 19:20:57

Chapman of the Giants

The MLB DFS First Look, complete with sortable odds, a pitcher breakdown, and team offense rankings, will help you get an early start on the upcoming DraftKings and FanDuel slates that are loaded into our MLB DFS optimizer, LineupHQ.

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MLB Odds & Schedule

Away Pitcher Handed Line A-Total Home Pitcher Handed Line H-Total G-Total Time (ET)
Washington Nationals MacKenzie Gore LHP 210 2.61 Atlanta Braves Chris Sale LHP -255 4.39 7.0 7:15 PM
Milwaukee Brewers Freddy Peralta RHP 110 3.25 San Diego Padres Nick Pivetta RHP -130 3.75 7.0 9:40 PM
St. Louis Cardinals Michael McGreevy RHP 124 3.58 San Francisco Giants Justin Verlander RHP -146 4.42 8.0 9:45 PM


Playbook

Pitcher Breakdown

Note: All statistics are from the 2025 season.
Pitcher Team Handed Opponent Line Total DK FD xwOBA xERA SIERA ERA K% BB% SS% GB% HC% Time (ET)
Chris Sale ATL LHP vs WAS -255 7.0 $9,500 $10,800 0.266 2.73 2.88 2.35 32% 6% 14% 40% 24% 7:15 PM
MacKenzie Gore WAS LHP at ATL 210 7.0 $7,700 $8,600 0.324 4.15 3.74 4.00 27% 9% 13% 37% 35% 7:15 PM
Nick Pivetta SDP RHP vs MIL -130 7.0 $8,500 $9,400 0.317 3.95 3.63 2.81 27% 7% 11% 33% 30% 9:40 PM
Freddy Peralta MIL RHP at SDP 110 7.0 $9,000 $10,300 0.292 3.31 3.72 2.65 28% 9% 13% 37% 28% 9:40 PM
Justin Verlander SFG RHP vs STL -146 8.0 $6,700 $8,200 0.324 4.15 4.47 3.75 21% 8% 11% 33% 33% 9:45 PM
Michael McGreevy STL RHP at SFG 124 8.0 $6,000 $7,700 0.335 4.47 4.45 4.08 15% 4% 8% 47% 31% 9:45 PM

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Offense Breakdown (Team Stats by Handedness)

Note: All statistics are from the 2025 season.
Offense Total TvsLHP TvsRHP Opponent Opp Pitcher Handed PvsLHB PvsRHB Time (ET)
Washington Nationals 2.61 0.270 0.315 at ATL Chris Sale LHP 0.253 0.271 7:15 PM
Atlanta Braves 4.39 0.309 0.323 vs. WAS MacKenzie Gore LHP 0.291 0.316 7:15 PM
Milwaukee Brewers 3.25 0.330 0.326 at SDP Nick Pivetta RHP 0.237 0.306 9:40 PM
San Diego Padres 3.75 0.305 0.334 vs. MIL Freddy Peralta RHP 0.278 0.297 9:40 PM
St. Louis Cardinals 3.58 0.300 0.304 at SFG Justin Verlander RHP 0.319 0.324 9:45 PM
San Francisco Giants 4.42 0.293 0.324 vs. STL Michael McGreevy RHP 0.363 0.242 9:45 PM

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Hitter Breakdown (Stats by Handedness)

Note: All statistics are from the 2025 season.
Batter Team Handed Order Total xwOBA xISO wOBA ISO wRC+ HC% BB% K% DK Pos FD Pos Opponent Opp Pitcher Handed P-wOBAvL P-xFIPvL P-K%vL P-wOBAvR P-xFIPvR P-K%vR Time (ET)
Nasim Nunez WAS SH 1 2.61 0.289 0.126 0.290 0.154 84 44% 13% 10% $3,300 2B/SS $2,100 SS/2B at ATL Chris Sale LHP 0.253 2.24 34% 0.271 2.96 33% 7:15 PM
C.J. Abrams WAS LH 2 2.61 0.322 0.161 0.288 0.114 82 25% 4% 26% $5,600 SS $3,100 SS at ATL Chris Sale LHP 0.253 2.24 34% 0.271 2.96 33% 7:15 PM
Andres Chaparro WAS RH 3 2.61 0.254 0.138 0.253 0.056 59 27% 12% 34% $2,100 1B $2,100 1B at ATL Chris Sale LHP 0.253 2.24 34% 0.271 2.96 33% 7:15 PM
Riley Adams WAS RH 4 2.61 0.289 0.154 0.241 0.131 50 41% 7% 41% $3,000 C $2,300 C at ATL Chris Sale LHP 0.253 2.24 34% 0.271 2.96 33% 7:15 PM
Dylan Crews WAS RH 5 2.61 0.323 0.172 0.216 0.042 34 36% 4% 24% $3,900 OF $2,700 OF at ATL Chris Sale LHP 0.253 2.24 34% 0.271 2.96 33% 7:15 PM
Paul DeJong WAS RH 6 2.61 0.272 0.161 0.282 0.279 78 42% 5% 40% $3,400 2B/3B $2,500 SS/3B at ATL Chris Sale LHP 0.253 2.24 34% 0.271 2.96 33% 7:15 PM
Brady House WAS RH 7 2.61 0.292 0.115 0.206 0.052 27 38% 1% 32% $3,000 3B $2,300 3B at ATL Chris Sale LHP 0.253 2.24 34% 0.271 2.96 33% 7:15 PM
Jacob Young WAS RH 8 2.61 0.297 0.070 0.280 0.047 77 22% 11% 19% $2,500 OF $2,200 OF at ATL Chris Sale LHP 0.253 2.24 34% 0.271 2.96 33% 7:15 PM
Robert Hassell WAS LH 9 2.61 0.290 0.154 0.248 0.033 55 25% 6% 31% $2,600 OF $2,300 OF at ATL Chris Sale LHP 0.253 2.24 34% 0.271 2.96 33% 7:15 PM
Jurickson Profar ATL SH 1 4.39 0.338 0.172 0.338 0.157 116 33% 9% 14% $5,500 OF $3,800 OF vs. WAS MacKenzie Gore LHP 0.291 3.68 26% 0.316 3.95 26% 7:15 PM
Matt Olson ATL LH 2 4.39 0.374 0.245 0.349 0.183 124 40% 8% 26% $5,000 1B $3,800 1B vs. WAS MacKenzie Gore LHP 0.291 3.68 26% 0.316 3.95 26% 7:15 PM
Ronald Acuna ATL RH 3 4.39 0.398 0.263 0.352 0.151 126 36% 19% 30% $6,000 OF $4,100 OF vs. WAS MacKenzie Gore LHP 0.291 3.68 26% 0.316 3.95 26% 7:15 PM
Ozzie Albies ATL SH 4 4.39 0.304 0.128 0.300 0.137 90 33% 3% 10% $4,500 2B $2,900 2B vs. WAS MacKenzie Gore LHP 0.291 3.68 26% 0.316 3.95 26% 7:15 PM
Ha-seong Kim ATL RH 5 4.39 0.303 0.117 0.310 0.098 96 31% 7% 16% $3,400 SS $2,700 SS/2B vs. WAS MacKenzie Gore LHP 0.291 3.68 26% 0.316 3.95 26% 7:15 PM
Marcell Ozuna ATL RH 6 4.39 0.363 0.215 0.330 0.135 111 37% 21% 22% $3,500 OF $3,000 OF vs. WAS MacKenzie Gore LHP 0.291 3.68 26% 0.316 3.95 26% 7:15 PM
Michael Harris ATL LH 7 4.39 0.315 0.160 0.258 0.122 62 22% 3% 22% $3,300 OF $2,900 OF vs. WAS MacKenzie Gore LHP 0.291 3.68 26% 0.316 3.95 26% 7:15 PM
Sandy Leon ATL SH 8 4.39 0.118 0.143 0.000 0.000 -100 0% 0% 25% $2,900 C $2,200 C vs. WAS MacKenzie Gore LHP 0.291 3.68 26% 0.316 3.95 26% 7:15 PM
Nacho Alvarez ATL RH 9 4.39 0.274 0.074 0.217 0.047 33 32% 8% 27% $2,800 3B $2,500 SS/2B/3B vs. WAS MacKenzie Gore LHP 0.291 3.68 26% 0.316 3.95 26% 7:15 PM
Sal Frelick MIL LH 1 3.25 0.311 0.090 0.321 0.111 106 23% 8% 14% $4,300 OF $3,200 OF at SDP Nick Pivetta RHP 0.237 3.62 29% 0.306 3.74 27% 9:40 PM
Jackson Chourio MIL RH 2 3.25 0.314 0.176 0.332 0.206 113 34% 5% 21% $5,100 OF $3,600 OF at SDP Nick Pivetta RHP 0.237 3.62 29% 0.306 3.74 27% 9:40 PM
Christian Yelich MIL LH 3 3.25 0.347 0.207 0.377 0.223 144 36% 12% 23% $5,300 OF $3,900 OF at SDP Nick Pivetta RHP 0.237 3.62 29% 0.306 3.74 27% 9:40 PM
William Contreras MIL RH 4 3.25 0.342 0.147 0.349 0.174 125 35% 11% 19% $4,900 C $3,200 C at SDP Nick Pivetta RHP 0.237 3.62 29% 0.306 3.74 27% 9:40 PM
Brice Turang MIL LH 5 3.25 0.342 0.173 0.326 0.139 110 35% 10% 19% $4,800 2B $3,500 2B at SDP Nick Pivetta RHP 0.237 3.62 29% 0.306 3.74 27% 9:40 PM
Caleb Durbin MIL RH 6 3.25 0.318 0.112 0.326 0.135 109 26% 6% 12% $3,600 3B $2,800 2B/3B at SDP Nick Pivetta RHP 0.237 3.62 29% 0.306 3.74 27% 9:40 PM
Jakob Bauers MIL LH 7 3.25 0.364 0.226 0.310 0.168 99 39% 13% 33% $3,200 1B/OF $2,800 1B/OF at SDP Nick Pivetta RHP 0.237 3.62 29% 0.306 3.74 27% 9:40 PM
Andrew Vaughn MIL RH 8 3.25 0.355 0.209 0.289 0.156 86 33% 6% 21% $3,400 1B $2,900 1B at SDP Nick Pivetta RHP 0.237 3.62 29% 0.306 3.74 27% 9:40 PM
Joey Ortiz MIL RH 9 3.25 0.280 0.081 0.280 0.104 78 25% 8% 16% $2,900 SS $2,600 3B/2B/SS at SDP Nick Pivetta RHP 0.237 3.62 29% 0.306 3.74 27% 9:40 PM
Fernando Tatis SDP RH 1 3.75 0.380 0.216 0.370 0.215 142 39% 9% 19% $5,800 OF $3,700 OF vs. MIL Freddy Peralta RHP 0.278 4.06 27% 0.297 3.44 31% 9:40 PM
Luis Arraez SDP LH 2 3.75 0.297 0.074 0.331 0.096 115 20% 5% 3% $3,900 1B/2B $2,700 1B/2B vs. MIL Freddy Peralta RHP 0.278 4.06 27% 0.297 3.44 31% 9:40 PM
Manny Machado SDP RH 3 3.75 0.364 0.222 0.338 0.178 121 40% 7% 19% $5,200 3B $3,700 3B vs. MIL Freddy Peralta RHP 0.278 4.06 27% 0.297 3.44 31% 9:40 PM
Jackson Merrill SDP LH 4 3.75 0.364 0.239 0.368 0.230 141 35% 6% 20% $4,100 OF $3,500 OF vs. MIL Freddy Peralta RHP 0.278 4.06 27% 0.297 3.44 31% 9:40 PM
Ramon Laureano SDP RH 5 3.75 0.374 0.252 0.340 0.201 120 43% 6% 28% $4,400 OF $3,100 OF vs. MIL Freddy Peralta RHP 0.278 4.06 27% 0.297 3.44 31% 9:40 PM
Gavin Sheets SDP LH 6 3.75 0.349 0.196 0.320 0.165 108 34% 9% 20% $3,700 1B/OF $2,800 1B/OF vs. MIL Freddy Peralta RHP 0.278 4.06 27% 0.297 3.44 31% 9:40 PM
Xander Bogaerts SDP RH 7 3.75 0.332 0.141 0.305 0.123 98 27% 7% 18% $3,200 SS $2,800 SS/2B vs. MIL Freddy Peralta RHP 0.278 4.06 27% 0.297 3.44 31% 9:40 PM
Jake Cronenworth SDP LH 8 3.75 0.324 0.125 0.342 0.170 123 28% 11% 19% $3,600 2B/SS $2,700 1B/2B vs. MIL Freddy Peralta RHP 0.278 4.06 27% 0.297 3.44 31% 9:40 PM
Freddy Fermin SDP RH 9 3.75 0.284 0.108 0.299 0.101 90 32% 5% 18% $2,600 C $2,500 C vs. MIL Freddy Peralta RHP 0.278 4.06 27% 0.297 3.44 31% 9:40 PM
Brendan Donovan STL LH 1 3.58 0.356 0.168 0.352 0.151 129 33% 8% 12% $3,500 2B $2,800 3B/2B/SS/OF at SFG Justin Verlander RHP 0.319 4.77 21% 0.324 4.60 20% 9:45 PM
Ivan Herrera STL RH 2 3.58 0.378 0.215 0.342 0.133 121 35% 8% 20% $4,700 C $3,300 C/OF at SFG Justin Verlander RHP 0.319 4.77 21% 0.324 4.60 20% 9:45 PM
Alec Burleson STL LH 3 3.58 0.355 0.204 0.353 0.180 129 38% 7% 13% $4,000 1B/OF $2,900 OF/1B at SFG Justin Verlander RHP 0.319 4.77 21% 0.324 4.60 20% 9:45 PM
Nolan Arenado STL RH 4 3.58 0.295 0.120 0.305 0.123 96 25% 7% 14% $3,300 3B $2,700 3B at SFG Justin Verlander RHP 0.319 4.77 21% 0.324 4.60 20% 9:45 PM
Lars Nootbaar STL LH 5 3.58 0.323 0.163 0.323 0.160 109 37% 12% 18% $3,400 OF $2,800 OF at SFG Justin Verlander RHP 0.319 4.77 21% 0.324 4.60 20% 9:45 PM
Thomas Saggese STL RH 6 3.58 0.286 0.113 0.286 0.081 84 28% 7% 26% $2,700 SS $2,400 3B/2B/SS at SFG Justin Verlander RHP 0.319 4.77 21% 0.324 4.60 20% 9:45 PM
Nolan Gorman STL LH 7 3.58 0.308 0.203 0.292 0.183 88 35% 11% 36% $3,100 1B/3B $2,700 2B/3B at SFG Justin Verlander RHP 0.319 4.77 21% 0.324 4.60 20% 9:45 PM
Pedro Pages STL RH 8 3.58 0.269 0.136 0.283 0.149 82 26% 6% 26% $3,100 C $2,600 C at SFG Justin Verlander RHP 0.319 4.77 21% 0.324 4.60 20% 9:45 PM
Victor Scott STL LH 9 3.58 0.288 0.088 0.266 0.102 70 21% 8% 23% $2,700 OF $2,400 OF at SFG Justin Verlander RHP 0.319 4.77 21% 0.324 4.60 20% 9:45 PM
Heliot Ramos SFG RH 1 4.42 0.325 0.167 0.306 0.133 97 32% 7% 24% $3,700 OF $3,100 OF vs. STL Michael McGreevy RHP 0.363 4.57 16% 0.242 3.59 15% 9:45 PM
Rafael Devers SFG LH 2 4.42 0.375 0.240 0.390 0.270 153 44% 16% 23% $5,400 1B $4,000 3B/1B vs. STL Michael McGreevy RHP 0.363 4.57 16% 0.242 3.59 15% 9:45 PM
Willy Adames SFG RH 3 4.42 0.335 0.212 0.346 0.211 124 35% 11% 25% $4,100 SS $3,700 SS vs. STL Michael McGreevy RHP 0.363 4.57 16% 0.242 3.59 15% 9:45 PM
Matt Chapman SFG RH 4 4.42 0.353 0.190 0.343 0.221 123 32% 11% 25% $4,300 3B $3,400 3B vs. STL Michael McGreevy RHP 0.363 4.57 16% 0.242 3.59 15% 9:45 PM
Bryce Eldridge SFG LH 5 4.42 0.450 0.457 0.210 0.077 32 83% 13% 44% $2,500 1B $2,700 OF vs. STL Michael McGreevy RHP 0.363 4.57 16% 0.242 3.59 15% 9:45 PM
Jung Hoo Lee SFG LH 6 4.42 0.326 0.109 0.326 0.133 111 28% 9% 8% $3,500 OF $3,000 OF vs. STL Michael McGreevy RHP 0.363 4.57 16% 0.242 3.59 15% 9:45 PM
Casey Schmitt SFG RH 7 4.42 0.331 0.173 0.314 0.182 103 37% 6% 23% $3,200 2B $2,800 3B/SS/2B/1B vs. STL Michael McGreevy RHP 0.363 4.57 16% 0.242 3.59 15% 9:45 PM
Patrick Bailey SFG SH 8 4.42 0.264 0.124 0.288 0.116 85 29% 8% 25% $2,800 C $2,800 C vs. STL Michael McGreevy RHP 0.363 4.57 16% 0.242 3.59 15% 9:45 PM
Drew Gilbert SFG LH 9 4.42 0.271 0.127 0.293 0.208 88 35% 5% 17% $3,400 OF $2,900 OF vs. STL Michael McGreevy RHP 0.363 4.57 16% 0.242 3.59 15% 9:45 PM

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About the Author

Notorious
Derek Farnsworth (Notorious)

Derek Farnsworth (aka Notorious) is a lead RotoGrinders Expert and one of the most recognizable names and faces in all of DFS. Before joining the RotoGrinders team, Derek received a Master’s Degree from the University of Utah. When he’s not busy providing content, he’s dominating the DFS industry as evidenced by his consistent top rankings in several sports and multiple Live Final appearances. Noto provides expert NBA, NFL, MLB, and PGA analysis for RotoGrinders Premium members on a daily basis and has also been nominated for five different Fantasy Sports Writer’s Association (FSWA) awards. Follow Noto on X – @RG_Notorious